- Basic information
- CohesinDB ID: CDBP00419474
- Locus: chr21-39368147-39369223
-
Data sourse: GSE206145, GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 71%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZNF316, TRIM24, TRIM28, ZMYM3, ZNF184, ZFX, BCOR, KDM1A
- Target gene symbol (double-evidenced CRMs): PSMG1,BRWD1
- Function elements
- Human SNPs: Lung_function_(FEV1/FVC)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
- Related loop:
chr21:39175000-39200000~~chr21:39350000-39375000,
chr21:39372709-39374761~~chr21:39387355-39389610,
chr21:39372834-39374834~~chr21:39387326-39389699,
chr21:39372912-39374798~~chr21:39387504-39389563,
chr21:39372914-39374485~~chr21:39387578-39389687,
chr21:39372946-39374777~~chr21:39387278-39389675,
chr21:39372954-39374915~~chr21:39387521-39389734,
chr21:39373048-39374478~~chr21:39387575-39389540,
chr21:39373064-39374576~~chr21:39387323-39389534,
chr21:39373100-39374555~~chr21:39387268-39389940,