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Basic information

CohesinDB ID: CDBP00419475

Locus: chr21-39369691-39371112

Data sourse: ENCSR230ZWH, ENCSR000BKV, GSE67783, GSE72082, GSE86191, GSE98367, ENCSR879KXD, ENCSR054FKH, GSE120943, ENCSR153HNT, GSE103477, GSE111537, GSE126755, GSE73207

Cell type: HCT-116, Monocytes, Hep-G2, THP-1, TF-1, OCI-AML-3, K-562, Liver, Neutrophil, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.878

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 51%, "14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, XBP1, FOXA1, SUZ12, RBFOX2, PBX2, UBTF, TFAP4, LYL1, ATF3, ZFP64, ZNF362, ATF4, MECOM, SMARCE1, ZSCAN4, JMJD1C, INTS11, ELF1, TRIM28, E2F5, RBM39, NFE2L2, LMO2, ESR1, OCA2, MLL, JUN, TCF12, CTCF, BAF155, E4F1, EP300, MNT, GATA6, DPF2, E2F6, TRIM24, SOX6, E2F4, ZNF512B, ZNF528, TEAD4, KMT2B, ZNF175, GATAD2A, EHMT2, RBPJ, EED, RUNX1T1, ID3, CTBP1, MTA2, ZBTB48, STAT1, NONO, MLLT3, DDX5, NBN, ARID3A, TBP, ERG, MYC, SMARCA4, ARID1B, RAD21, GRHL3, RXRA, FOXK2, GABPA, ZNF614, XRCC5, IKZF1, LEF1, NFE2, RCOR1, VDR, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, TBL1XR1, EZH2, PHF8, SPI1, IRF1, HDAC2, GATA2, INTS13, ZNF644, ZSCAN29, FLI1, DRAP1, NR2C2, SMARCA5, EP400, NFIL3, NCOA2, ZNF554, ATF1, RUNX1, THAP11, SMC1A, CBX1, HDAC1, CEBPA, ZFX, ZMIZ1, ZNF18, PRDM10, ZBTB2, ZNF384, CREBBP, BRD9, RUNX2, OSR2, PBX4, ARNT, BACH1, ATF2, ZEB2, HMBOX1, CBFA2T3, FOS, CDK8, MED1, TEAD3, PML, CEBPD, MYB, ZMYM3, SMAD1, VEZF1, TAF7, NCOA1, L3MBTL2, GTF3C2, EVI1, STAT5A, KLF16, ZNF22, SP1, BCL11A, NR4A1, HNF4A, REST, ZBTB7A, ATF7, HNRNPLL, AFF1, TCF3, BCOR, PHIP, MLLT1, NFATC3, SKI, CBX3, MTA3, RBBP5, CREM, MEIS1, E2F8, EBF1, GTF2B, ZBTB33, MEF2C, CDK9, HOXB13, ZKSCAN1, KDM1A, ZNF589, RELA, JUNB, NEUROD1, ZNF148, TCF4, SKIL, ZFP36, HIF1A, MGA, TAL1, MAX, GATA1, MTA1, CEBPG, GFI1B, NR2F2, NR2F1, TCF7L2, KDM5B, PKNOX1, MED, ELF3, BHLHE40, AR, ARID4B, TAF1, ZBTB16, ZBTB40, ZNF366, EGR1, MYNN, NCOR1, RNF2, BRD4, ILF3, JUND, NOTCH3, ZBTB26, MAZ, IRF9, MEF2D, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): PSMG1,BRWD1

Function elements

Human SNPs: Platelet_count

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 15

Related genes and loops

Related gene: ENSG00000183527, ENSG00000185658,

eachgene

Deatailed information for cohesin site CDBP00419475