- Basic information
- CohesinDB ID: CDBP00419484
- Locus: chr21-39398076-39398420
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 51%,
"4_Tx": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SKI, NCOA2, PGR, SMC1A, CHD8, FOXA2, CEBPA, MYCN, TOP2A, SOX2, ZFX, POU2F2, XBP1, SMAD3, FOXA1, ZBTB33, MEF2C, HOXB13, ERG, RELA, CREBBP, MYC, OSR2, RAD21, PRDM1, TOP1, HIF1A, SOX11, NKX2-1, GATA3, HMBOX1, GABPA, STAT3, MAX, XRCC5, NRIP1, ZNF143, CDK8, FOS, MECOM, VDR, NR3C1, JMJD1C, CEBPB, TEAD3, TEAD1, SP7, MYB, SCRT2, INTS11, NCOA3, KDM5B, ESR1, MLL, OCA2, NCOA1, FEZF1, CTCF, TCF12, RBM22, SPI1, AR, INTS13, TRIM24, MXD3, FLI1, NOTCH3, SCRT1, BRD4, TCF3, MAZ, TEAD4, KMT2B, STAG1, AHR, EED
- Target gene symbol (double-evidenced CRMs): GET1,ERG,B3GALT5,BRWD1,GET1-SH3BGR,ETS2,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000157554,
ENSG00000157557,
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000183778,
- Related loop:
chr21:34350000-34375000~~chr21:39375000-39400000,
chr21:38500000-38525000~~chr21:39375000-39400000,
chr21:38575000-38600000~~chr21:39375000-39400000,
chr21:38750000-38775000~~chr21:39375000-39400000,
chr21:38775000-38800000~~chr21:39375000-39400000,
chr21:38800000-38825000~~chr21:39375000-39400000,
chr21:38850000-38875000~~chr21:39400000-39425000,
chr21:38900000-38925000~~chr21:39375000-39400000,
chr21:38925000-38950000~~chr21:39375000-39400000,
chr21:39000000-39025000~~chr21:39375000-39400000,
chr21:39150000-39175000~~chr21:39375000-39400000,
chr21:39175000-39200000~~chr21:39375000-39400000,
chr21:39175000-39200000~~chr21:39400000-39425000,
chr21:39200000-39225000~~chr21:39375000-39400000,
chr21:39200000-39225000~~chr21:39400000-39425000,
chr21:39225000-39250000~~chr21:39375000-39400000,
chr21:39225000-39250000~~chr21:39400000-39425000,
chr21:39275000-39300000~~chr21:39375000-39400000,
chr21:39275000-39300000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39375000-39400000~~chr21:39625000-39650000,
chr21:39400000-39425000~~chr21:39700000-39725000,