- Basic information
- CohesinDB ID: CDBP00419492
- Locus: chr21-39413873-39414796
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Data sourse: GSE67783, GSE86191, GSE98367, GSE206145, GSE120943, ENCSR153HNT
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Cell type: RPE, HCT-116, Monocytes, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 55%,
"5_TxWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, CHD8, ZSCAN5D, POU5F1, ZNF263, MYCN, HDAC1, ZFX, XBP1, WT1, ZBTB48, ZBTB33, DDX5, ERG, RELA, HDGF, ZBTB2, ATF3, MYC, ARID1B, ZNF184, ARNT, HIF1A, ZSCAN4, ZNF143, CDK8, MITF, IKZF1, MED1, NR2F1, ESR1, TP53, CTCF, RBM22, AR, PAX3-FOXO1, DPF2, REST, ZBTB42, NOTCH3, BRD4, ZNF528, ZNF350, SMC3, ZNF24, STAG1, EED
- Target gene symbol (double-evidenced CRMs): GET1,PSMG1,LCA5L,BRWD1,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
- Related loop:
chr21:38850000-38875000~~chr21:39400000-39425000,
chr21:39175000-39200000~~chr21:39400000-39425000,
chr21:39200000-39225000~~chr21:39400000-39425000,
chr21:39225000-39250000~~chr21:39400000-39425000,
chr21:39275000-39300000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39400000-39425000~~chr21:39700000-39725000,