- Basic information
- CohesinDB ID: CDBP00419499
- Locus: chr21-39425591-39426058
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Data sourse: GSE50893, GSE67783, GSE86191
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Cell type: HCT-116, HSPC, SNYDER
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 83%,
"5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, BCL6, ZFX, XBP1, ERG3, YY1, RELA, GRHL3, ARNT, XRCC5, NRIP1, ZNF143, ZNF467, NCOA3, EZH2, ZNF334, CTCF, RBM22, AR, NOTCH3, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,BRWD1,LCA5L,HMGN1,GET1,ETS2,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000157557,
ENSG00000183527,
ENSG00000185658,
ENSG00000205581,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
- Related loop:
chr21:38800000-38825000~~chr21:39425000-39450000,
chr21:38850000-38875000~~chr21:39400000-39425000,
chr21:39000000-39025000~~chr21:39425000-39450000,
chr21:39175000-39200000~~chr21:39400000-39425000,
chr21:39175000-39200000~~chr21:39425000-39450000,
chr21:39200000-39225000~~chr21:39400000-39425000,
chr21:39200000-39225000~~chr21:39425000-39450000,
chr21:39225000-39250000~~chr21:39400000-39425000,
chr21:39225000-39250000~~chr21:39425000-39450000,
chr21:39275000-39300000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39400000-39425000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39325000-39350000~~chr21:39425000-39450000,
chr21:39400000-39425000~~chr21:39700000-39725000,