- Basic information
- CohesinDB ID: CDBP00419518
- Locus: chr21-39496169-39496513
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 88%,
"5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZBTB48, TRP47, OGG1, FOXA2
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 25
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
- Related loop:
chr21:39500000-39525000~~chr21:39600000-39625000,
chr21:39500000-39525000~~chr21:39675000-39700000,
chr21:39500000-39525000~~chr21:39700000-39725000,
chr21:39500000-39525000~~chr21:39775000-39800000,
chr21:39500000-39525000~~chr21:39850000-39875000,
chr21:39500000-39525000~~chr21:39900000-39925000,
chr21:39500000-39525000~~chr21:39925000-39950000,
chr21:39500000-39525000~~chr21:40025000-40050000,
chr21:39500000-39525000~~chr21:40050000-40075000,
chr21:39500000-39525000~~chr21:40100000-40125000,
chr21:39500000-39525000~~chr21:40125000-40150000,
chr21:39500000-39525000~~chr21:40350000-40375000,
chr21:39500000-39525000~~chr21:41075000-41100000,