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Basic information

CohesinDB ID: CDBP00419520

Locus: chr21-39502548-39502970

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 73%, "7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SMC1A, BRD1, CEBPA, MYCN, POU5F1, EBF1, KDM4C, ZFX, XBP1, ZBTB48, WT1, TET2, ERG, YY1, RELA, KDM1A, MYC, CDK6, SP140, GATA3, PRDM9, GABPA, STAT3, MAX, TP63, GATA1, CDK8, MITF, JMJD1C, CREB1, EZH2, ESR1, CTCF, SPI1, BCL11A, NR4A1, RXR, E2F6, FLI1, HSF1, MYNN, HNRNPLL, NOTCH3, BRD4, MAZ, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): PCP4,SH3BGR,B3GALT5,GET1-SH3BGR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 5

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000183036,

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Deatailed information for cohesin site CDBP00419520