Browse_each

Basic information

CohesinDB ID: CDBP00419522

Locus: chr21-39509959-39510524

Data sourse: GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, GSE116344, GSE25021

Cell type: MCF-7, RPE, Fibroblast, HCT-116, Monocytes, RH4, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 76%, "5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRP47, OGG1, SMC1A, SP140, ZBTB48, WT1, FOXA1, ZSCAN4

Target gene symbol (double-evidenced CRMs): PCP4,B3GALT5,GET1-SH3BGR,SH3BGR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 20

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000183036,

eachgene

Deatailed information for cohesin site CDBP00419522