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Basic information

CohesinDB ID: CDBP00419523

Locus: chr21-39511165-39511517

Data sourse: GSE25021, ENCSR153HNT

Cell type: K-562, MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 72%, "5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, ZNF195, XBP1, PATZ1, FOXA1, SUZ12, ZBTB7B, HDGF, TSC22D4, BMI1, ATF3, ZBTB5, ZNF444, ZSCAN4, CDC5L, ELF1, BCLAF1, LMO2, ESR1, OCA2, CTCF, E4F1, MNT, DPF2, TRIM24, GLI4, ZNF410, ZNF512B, ZNF776, ZNF528, ZNF280A, PLRG1, EHMT2, YBX1, POU2F2, CHD8, NANOG, MYCN, ZNF239, POU5F1, CTBP1, ZSCAN21, ZBTB1, MTA2, ASH1L, ZBTB48, ZSCAN5A, NONO, DDX5, ERG2, PHB2, MYC, SMARCA4, RFX1, ARID1B, GRHL3, FOXK2, ZNF8, RCOR1, ZNF639, ESRRA, CREB1, YBX3, ZNF292, HES1, IRF1, HDAC2, SSRP1, GATAD2B, ZNF146, SMARCA5, SALL2, SMC1A, HDAC1, ZNF707, ZFX, NFXL1, ERG3, TRIM22, MYBL2, ZNF184, NFIB, ZBTB10, SNIP1, ZEB2, SUPT5H, NCOA1, SETDB1, SP1, GSPT2, ARID2, FOXP1, MLLT1, STAG1, NCOA4, ZNF207, MTA3, FOXA2, TBL1X, ZSCAN16, GTF2B, ZNF662, ZBTB33, ZKSCAN1, YY1, RELA, TARDBP, NEUROD1, ZNF266, ZNF521, HIF1A, ZNF311, ZNF143, MTA1, ZNF592, NCOA3, ZNF544, ZNF791, KDM5B, ZNF687, PKNOX1, EGR2, AR, EGLN2, HSF1, RNF2, NOTCH3, BRD4, MAZ, ZSCAN23, ZNF24

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,SH3BGR,PCP4,B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 90

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000183036,

eachgene

Deatailed information for cohesin site CDBP00419523