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Basic information

CohesinDB ID: CDBP00419527

Locus: chr21-39525261-39526244

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015

Cell type: MCF-7, RPE, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 46%, "5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM25, POU2F2, CEBPA, NKX2-2, MYCN, ZNF263, RBPJ, ZFX, CTBP1, MTA3, CREM, ZBTB48, WT1, FOXA1, TET2, ERG, RELA, ATF3, MYC, CTCFL, RUNX3, SP140, RXRA, NKX2-1, ATF4, PRDM9, GABPA, MECOM, STAT3, MAX, PAX5, SP2, IKZF1, SNRNP70, DNMT3B, RCOR1, TERF1, TRIM28, KDM5B, EZH2, ESR1, L3MBTL2, GABPB1, CTCF, TCF12, SP1, SPI1, HNF4A, AR, ZBTB40, REST, ZNF479, GATAD2B, HCFC1, BRD4, MAZ, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183778,

eachgene

Deatailed information for cohesin site CDBP00419527