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Basic information

CohesinDB ID: CDBP00419528

Locus: chr21-39526693-39532966

Data sourse: ENCSR000BLD, ShirahigeLab-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, GSE115602, ENCSR000BTU, GSE67783, ENCSR000BKV, GSE86191, GSE76893, ShirahigeLab-NatGen2015, ENCSR703TNG, ShirahigeLab, ENCSR000EHX, ENCSR984DZW, ENCSR000BTQ, GSE110061, GSE129526, ENCSR153HNT, GSE83726

Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, RH4, Ishikawa, A-549, DKO, SK-N-SH, K-562, Liver, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 14% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.844

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 32%, "7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MBD3, NFIA, PGR, MEIS2, FOXA1, SUZ12, RXRB, PBX2, ZFHX2, HNRNPK, TFAP4, THRB, NFIC, MXD4, SMARCE1, CDX2, KLF5, TEAD1, ELF1, TRIM28, ETV1, RCOR2, ESR1, CTCF, JUN, TCF12, EP300, BAF155, MNT, GATA6, SOX5, DPF2, SOX4, CREB3, E2F1, NR5A2, TEAD4, FOXA3, GATAD2A, PDX1, RBPJ, TFAP2C, GTF2F1, EHMT2, POU2F2, BRD1, ZNF263, MYCN, CTBP1, ZNF317, ZBTB48, DUX4, SRF, GATAD1, SAP130, ERG2, HNF4G, ERG, MIER1, MYC, ONECUT1, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, ZNF614, XRCC5, PRDM14, RCOR1, NR2F6, NR3C1, ESRRA, CEBPB, CREB1, EZH2, GRHL2, TRPS1, GABPB1, SPI1, MIXL1, ZNF257, HDAC2, GATA2, ZNF644, MXD3, FLI1, HCFC1, NR2C2, ZNF490, NFIL3, NCOA2, ETV5, RUNX1, MAFG, CBX1, BCL6, EZH2phosphoT487, CEBPA, SOX13, ZFX, SIN3A, SMAD3, ZNF770, ERG3, SP5, RARA, CREBBP, ZXDC, NRF1, NFIB, ARNT, ZNF48, PRDM9, SMAD4, FOXM1, FOS, CDK8, MED1, ZEB1, TEAD3, SCRT2, PIAS1, NR1H2, KLF9, C11orf30, MAFK, SP1, TFAP2A, NIPBL, HNF4A, IKZF5, REST, ZBTB7A, ASH2L, HNRNPLL, CTBP2, AFF1, MBD2, FOXP1, SMC3, NCOR2, STAG1, ETV4, CBFA2T2, ZNF316, FOXA2, MIER2, WT1, MAFF, HOXB13, ZNF580, KDM1A, YY1, RELA, NEUROD1, SP140, ZFP36, HIF1A, GATA3, KLF15, TAL1, MAX, MAF1, NRIP1, GATA1, MTA1, ZNF143, PLAG1, TLE3, KLF4, CEBPG, NCOA3, NR2F2, NR2F1, KDM5B, ZNF687, TP53, PKNOX1, ZNF334, ZSCAN22, MYOD1, EGR2, ELF3, ARID4B, PAX3-FOXO1, AR, ZNF579, RXR, EGLN2, EGR1, ZBTB26, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000183778,

eachgene

Deatailed information for cohesin site CDBP00419528