- Basic information
- CohesinDB ID: CDBP00419536
- Locus: chr21-39565337-39565914
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Data sourse: GSE120943, GSE67783, GSE98367
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Cell type: Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, NME2, XBP1, FOXA1, SUZ12, PBX2, ZNF28, ZBTB7B, HDGF, ATF3, NFIC, CHD7, PRDM1, ZNF444, DPF1, ZSCAN4, MITF, ZNF320, ZNF467, TEAD1, BCLAF1, ZNF217, ESR1, PITX3, ZIK1, CTCF, JUN, TCF12, EP300, E4F1, BAF155, DPF2, E2F6, IRF4, RFX5, ZNF512B, ZNF776, E2F1, ZNF350, TEAD4, PDX1, TFAP2C, EHMT2, GLIS1, NANOG, RUNX1T1, CTBP1, ZBTB48, STAT1, NONO, ERG, PBX1, ASCL1, MYC, RFX1, RAD21, GRHL3, NKX2-1, GABPA, STAT3, NKX3-1, ZNF398, IKZF1, RCOR1, HNRNPH1, DACH1, VDR, NR3C1, CEBPB, CREB1, EZH2, GRHL2, EBF3, TRPS1, SPI1, HDAC2, GATA2, GATAD2B, RUNX1, CBX1, SMC1A, NKX2-2, SIN3A, ZFX, PCBP2, ERG3, CREBBP, ZNF384, RUNX2, ARNT, NFIB, FOS, MED1, PIAS1, KLF9, USF1, SP1, TFAP2A, POU2F3, ASH2L, CTBP2, TCF3, FOXP1, SMC3, STAG1, FOXA2, CHD2, WT1, ZNF662, HOXB13, ZKSCAN1, RELA, NEUROD1, ZNF148, MCM3, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, GATA1, MTA1, TCF7L2, KDM5B, TP53, PKNOX1, ZNF687, MYOD1, EGR2, AR, PAX3-FOXO1, EGLN2, ZNF366, EGR1, HSF1, NCOR1, BRD4, SCRT1, CUX1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 3
- Related genes and loops