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Basic information

CohesinDB ID: CDBP00419545

Locus: chr21-39597648-39597957

Data sourse: GSE86191, GSE68388

Cell type: HCT-116, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 60%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, FOXA1, SUZ12, ZFHX2, ATF3, MORC2, TEAD1, ESR1, CTCF, JUN, E2F6, ZNF528, PDX1, TFAP2C, GLIS1, ZNF425, POU2F2, MYCN, ZNF263, TOP2A, POU5F1, ZNF239, DUX4, ZBTB48, ERG2, ERG, ASCL1, ETS1, MYC, SMARCA4, GABPA, STAT3, XRCC5, NKX3-1, RCOR1, NR3C1, ESRRA, CREB1, EZH2, ZHX2, SPI1, GATA2, SIX2, RUNX1, SMC1A, NKX2-2, ZFX, TET2, ERG3, ZNF384, OSR2, ARNT, ATF2, FOS, MED1, PIAS1, ZMYM3, KLF9, BCL11A, REST, RBM25, POU2F3, AATF, SMC3, STAG1, TRP47, CBFA2T2, TBL1X, FOXA2, CBX3, RBBP5, WT1, HOXB13, KDM1A, YY1, RELA, SP140, OTX2, GATA3, MAX, ZNF143, HAND2, CBX2, TLE3, NR2F1, NEUROG2, TP53, ZNF334, MYOD1, EGR2, PHOX2B, AR, RXR, ZBTB42, HEXIM1, HSF1, NOTCH3, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 26

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183778,

eachgene

Deatailed information for cohesin site CDBP00419545