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Basic information

CohesinDB ID: CDBP00419550

Locus: chr21-39608787-39609235

Data sourse: GSE206145, GSE206145-GSE177045, GSE86191

Cell type: MCF-7, HCT-116, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 38%, "15_Quies": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, GLIS1, BRD1, ZNF263, MYCN, ZFX, ZBTB48, WT1, TET2, ERG, ATF3, MYC, SP140, TAL1, EZH2, CTCF, SPI1, PAX3-FOXO1, HSF1, MAZ, STAG1

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,B3GALT5,ERG,ETS2,BRWD1,PCP4,SH3BGR,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000157554, ENSG00000157557, ENSG00000185658, ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000183036, ENSG00000157601,

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Deatailed information for cohesin site CDBP00419550