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Basic information

CohesinDB ID: CDBP00419553

Locus: chr21-39625225-39625791

Data sourse: ENCSR000BLD, GSE68388

Cell type: H1-hESC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 51%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NCOA2, PGR, CHD8, NANOG, FOXA2, NKX2-2, ZFX, HNF1A, GTF2B, SMAD3, ZNF317, FOXA1, ERG3, HOXB13, MLL4, KDM1A, ERG, RELA, CREBBP, ASCL1, CDK6, EOMES, RAD21, ARNT, GRHL3, HIF1A, OTX2, GATA3, STAT3, MAX, NKX3-1, HAND2, KLF4, ZEB1, NCOA3, KLF6, TCF7L2, ESR1, HNF1B, NR1H2, TP53, EBF3, ZNF140, PHOX2B, ELF3, BRD2, T, EP300, BCL11A, SPI1, PAX3-FOXO1, IRF1, AR, GATA6, SOX9, GATA2, HDAC2, ASH2L, BRD4, PHIP, TEAD4, PDX1, AHR

Target gene symbol (double-evidenced CRMs): B3GALT5,BRWD1,GET1,PSMG1,GET1-SH3BGR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000183527, ENSG00000185658, ENSG00000285815, ENSG00000182093, ENSG00000183778,

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Deatailed information for cohesin site CDBP00419553