- Basic information
- CohesinDB ID: CDBP00419556
- Locus: chr21-39636297-39636947
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Data sourse: GSE105028, GSE25021, GSE67783, GSE86191
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Cell type: MCF-7, HCT-116, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 28%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, SOX2, XBP1, HNF1A, FOXA1, PBX2, ZFHX2, TFAP4, CHD7, MORC2, ZNF189, TP63, CDX2, KLF5, TEAD1, TRIM28, KLF6, SAP30, ESR1, HNF1B, ZFP91, CTCF, TCF12, EP300, KLF1, BAF155, MNT, SOX9, E2F6, ZNF512B, ZNF528, TEAD4, PDX1, TFAP2C, EED, GLIS1, NANOG, CHD8, BRD1, ZNF263, POU5F1, MYCN, TOP2A, CTBP1, ZNF317, ZBTB17, ZBTB48, DDX5, ERG2, HOXC5, ERG, ASCL1, ONECUT1, MYC, EOMES, RAD21, GRHL3, PROX1, NKX2-1, GABPA, STAT3, NKX3-1, DACH1, NR3C1, CEBPB, CREB1, EZH2, GRHL2, ZHX2, IRF1, KLF17, HDAC2, GATA2, SIX2, SREBF1, NCOA2, RUNX1, CBX1, NKX2-2, SIN3A, ZFX, SMAD3, ERG3, CREBBP, PBX4, ARNT, ATF2, MAFB, FOS, CHD1, MED1, PIAS1, USF1, NIPBL, SP1, HNF4A, POU2F3, ASH2L, CTBP2, PHIP, BCOR, FOXP1, AATF, SMC3, STAG1, ZNF283, CBFA2T2, FOXA2, ZNF207, RBBP5, WT1, HOXB13, KDM1A, YY1, RELA, ZIC2, HIF1A, GATA3, KLF15, MAX, NRIP1, ZNF143, MTA1, KLF4, ZNF512, TCF7L2, TP53, PKNOX1, MYOD1, EGR2, T, ELF3, AR, ZNF366, ZBTB26, NCOR1, BRD4, JUND, AHR
- Target gene symbol (double-evidenced CRMs): B3GALT5,GET1,PSMG1,BRWD1,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000183778,
- Related loop:
chr21:39175000-39200000~~chr21:39625000-39650000,
chr21:39375000-39400000~~chr21:39625000-39650000,
chr21:39517354-39519438~~chr21:39629845-39631913,
chr21:39525000-39550000~~chr21:39625000-39650000,
chr21:39625000-39650000~~chr21:41650000-41675000,
chr21:39625000-39650000~~chr21:42975000-43000000,
chr21:39633375-39634630~~chr21:39715081-39716789,