- Basic information
- CohesinDB ID: CDBP00419561
- Locus: chr21-39643132-39643834
-
Data sourse: GSE67783, GSE105028, ENCSR198ZYJ, GSE83726, GSE116344
-
Cell type: Neurons-H1, RH4, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 28%,
"7_Enh": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NANOG, PGR, BRD1, FOXA2, MYCN, NKX2-2, ZNF263, SIN3A, ZFX, SOX2, ZNF534, ZBTB48, WT1, STAT1, FOXA1, FOXF1, ZSCAN5A, KDM4B, CDK9, PBX2, HOXB13, KDM1A, ERG, RELA, CREBBP, ZNF384, ASCL1, MYC, GR, RAD21, CHD7, ARNT, HIF1A, ZIC2, SP140, NKX2-1, GATA3, TAL1, MAX, MAFB, NKX3-1, STAT3, NRIP1, MED1, NR3C1, CEBPB, MYOG, ESRRA, TEAD1, CREB1, TFAP2C, EZH2, SAP30, ESR1, PKNOX1, STAG1, GRHL2, SETDB1, MYOD1, CTCF, TCF12, ELF3, EP300, SPI1, BAF155, TFAP2A, PAX3-FOXO1, GATA6, T, MNT, USF1, GATA2, IRF4, POU2F3, FLI1, HSF1, NOTCH3, BRD4, MAZ, MYF5, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): BRWD1,PSMG1,B3GALT5,GET1-SH3BGR,GET1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000183778,
- Related loop:
chr21:39175000-39200000~~chr21:39625000-39650000,
chr21:39375000-39400000~~chr21:39625000-39650000,
chr21:39525000-39550000~~chr21:39625000-39650000,
chr21:39625000-39650000~~chr21:41650000-41675000,
chr21:39625000-39650000~~chr21:42975000-43000000,