- Basic information
- CohesinDB ID: CDBP00419562
- Locus: chr21-39644110-39644390
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Data sourse: GSE206145-GSE177045, GSE72082
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 30%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, PGR, BRD1, FOXA2, MYCN, NKX2-2, ZNF263, SIN3A, ZFX, SOX2, ZNF534, ZBTB48, WT1, STAT1, FOXA1, FOXF1, ZSCAN5A, KDM4B, CDK9, PBX2, HOXB13, KDM1A, ERG, RELA, CREBBP, ZNF384, ASCL1, MYC, GR, RAD21, CHD7, ARNT, HIF1A, ZIC2, SP140, NKX2-1, GATA3, TAL1, MAX, MAFB, NKX3-1, STAT3, NRIP1, MED1, NR3C1, CEBPB, MYOG, ESRRA, TEAD1, CREB1, TFAP2C, EZH2, SAP30, ESR1, PKNOX1, STAG1, GRHL2, SETDB1, MYOD1, CTCF, TCF12, ELF3, EP300, SPI1, BAF155, TFAP2A, PAX3-FOXO1, GATA6, T, MNT, USF1, GATA2, IRF4, POU2F3, FLI1, HSF1, NOTCH3, BRD4, MAZ, MYF5, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): BRWD1,GET1-SH3BGR,B3GALT5,GET1,PSMG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000183778,
- Related loop:
chr21:39175000-39200000~~chr21:39625000-39650000,
chr21:39375000-39400000~~chr21:39625000-39650000,
chr21:39525000-39550000~~chr21:39625000-39650000,
chr21:39625000-39650000~~chr21:41650000-41675000,
chr21:39625000-39650000~~chr21:42975000-43000000,