- Basic information
- CohesinDB ID: CDBP00419565
- Locus: chr21-39655291-39655839
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Data sourse: GSE206145-NatGen2015, GSE86191
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Cell type: Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 44%,
"5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, NME2, HNF1A, PATZ1, FOXA1, SUZ12, ATF3, NFIC, BMI1, ZFP64, CHD7, ZNF189, MITF, CDX2, ZNF467, MYOG, ZNF629, ELF1, TRIM28, KLF6, SNAI2, ETV1, ESR1, HNF1B, OCA2, PITX3, USF2, CTCF, JUN, TCF12, BAF155, EP300, ZBTB20, MNT, GATA6, SOX4, E2F6, IRF4, RAD51, E2F1, TEAD4, ZNF92, GTF2F1, PDX1, TFAP2C, GLIS1, CHD8, BRD1, ZNF263, MYCN, TOP2A, BRD3, POU5F1, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, DUX4, STAT1, ZNF134, ERG, HOXC5, ZBTB21, CHD4, ASCL1, ETS1, MYC, RAD21, RXRA, STAT3, NKX3-1, RCOR1, DNMT3B, NR3C1, CEBPB, CREB1, EZH2, KLF8, BMPR1A, GRHL2, EBF3, ZHX2, EHF, IRF1, KLF17, GATA2, SIX2, MXI1, NCOA2, ZNF554, MYF5, RUNX1, EZH2phosphoT487, NKX2-2, LDB1, SIN3A, ZFX, SMAD3, ZBTB12, PCBP2, TET2, ERG3, CBX8, TWIST1, PRDM10, CREBBP, ZNF384, CBX4, RUNX2, OSR2, ARNT, PBX4, NRF1, DAXX, ATF2, PRDM9, ZNF518A, CBFA2T3, PBX3, ZNF10, FOS, SNRNP70, MED1, ZEB1, SCRT2, PIAS1, ZMYM3, USF1, BCL11A, SP1, REST, ZNF479, RBM25, ATF7, BCOR, NCOR2, STAG1, CBFA2T2, FOXA2, EBF1, CHD2, SS18, ZNF600, ZSCAN16, ZNF692, WT1, FOXF1, HOXB13, KDM1A, YY1, RELA, MCM3, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, HAND2, CBX2, PLAG1, KLF4, ZFP69B, NR2F2, NEUROG2, KDM5B, TP53, ZNF334, MYOD1, PHOX2B, ELF3, BRD2, BHLHE40, AR, TAF1, EGLN2, ZNF366, ZBTB42, RNF2, SCRT1, BRD4, JUND, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): PSMG1,B3GALT5,BRWD1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 1
- Related genes and loops