- Basic information
- CohesinDB ID: CDBP00419577
- Locus: chr21-39681815-39682299
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Data sourse: ENCSR853VWZ, GSE72082, ENCSR703TNG, GSE206145, ENCSR335RKQ, GSE206145-NatGen2015, ENCSR767DFK, ENCSR199XBQ, ENCSR984DZW, ENCSR330ELC, ENCSR217ELF
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Cell type: MCF-7, Fibroblast, A-549, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 75%,
"14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, GLIS1, PGR, CBX1, FOXA2, CEBPA, POU5F1, NKX2-2, SOX2, SOX13, CTBP1, SIN3A, NME2, SMAD3, FOXA1, HLF, RELA, ZXDC, ZNF384, CREBBP, TARDBP, JUNB, GR, CHD7, ZNF24, GRHL3, NKX2-1, GATA3, STAT3, MAX, SMARCE1, NKX3-1, FOS, RCOR1, MED1, VDR, NR3C1, CEBPB, CEBPG, NR2F2, CREB1, ESR1, GRHL2, CTCF, TCF12, ELF3, JUN, AR, DPF2, GATA2, GATAD2B, ATF7, BRD4, SMARCA5, FOXP1, CUX1, NFIL3, FOXA3, GATAD2A, PDX1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops