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Basic information

CohesinDB ID: CDBP00419582

Locus: chr21-39701576-39703321

Data sourse: ENCSR703TNG, GSE206145-GSE177045, GSE72082, GSE115602

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 69% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 51%, "9_Het": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, CHD8, SIN3A, STAT1, FOXA1, ZNF513, HOXB13, ERG, RELA, CREBBP, ZNF384, AHR, NFIB, HIF1A, ARNT, NKX2-1, GATA3, GABPA, NRIP1, NKX3-1, VDR, TLE3, NR3C1, ESRRA, NCOA3, NR2F2, TEAD1, CREB1, PIAS1, TCF7L2, EZH2, ESR1, GRHL2, TRPS1, CTCF, TCF12, BAF155, TFAP2A, AR, HDAC2, GATA2, ASH2L, BRD4, CTBP2, FOXP1, NR5A2, NCOA2, PDX1, TFAP2C

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,BRWD1,B3GALT5,MX1,PSMG1,SH3BGR,LCA5L,GET1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183527, ENSG00000185658, ENSG00000285815, ENSG00000182093, ENSG00000157578, ENSG00000185437, ENSG00000183778, ENSG00000157601,

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Deatailed information for cohesin site CDBP00419582