- Basic information
- CohesinDB ID: CDBP00419585
- Locus: chr21-39710803-39711977
-
Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015
-
Cell type: MCF-7, RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 57%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU2F2, CHD8, CBX1, SMC1A, ZNF263, MYCN, EZH2phosphoT487, SIN3A, ZFX, NME2, XBP1, HNF1A, RBBP5, NKX2-2, SMAD3, FOXA1, WT1, PBX2, TRIM22, ZNF549, RELA, CREBBP, ASCL1, AHR, MYC, RFX1, RAD21, GRHL3, HIF1A, ARNT, ZNF444, NKX2-1, GATA3, TAL1, MAX, NRIP1, FOS, ZNF143, CEBPG, CEBPB, NR3C1, NCOA3, CREB1, SMAD1, EZH2, ESR1, PKNOX1, TP53, ZNF334, TBX5, MYOD1, NFKB1, CTCF, JUN, BCL11A, ARRB1, AR, GATA6, HNRNPLL, BRD4, MAZ, RELB, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): MX1,B3GALT5,SH3BGR,BRWD1,PSMG1,GET1-SH3BGR,LCA5L,GET1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
ENSG00000157601,
- Related loop:
chr21:39100000-39125000~~chr21:39700000-39725000,
chr21:39150000-39175000~~chr21:39700000-39725000,
chr21:39225000-39250000~~chr21:39700000-39725000,
chr21:39300000-39325000~~chr21:39700000-39725000,
chr21:39400000-39425000~~chr21:39700000-39725000,
chr21:39500000-39525000~~chr21:39700000-39725000,
chr21:39517168-39519542~~chr21:39705393-39707110,
chr21:39517168-39519542~~chr21:39715040-39717158,
chr21:39517259-39519458~~chr21:39714980-39716790,
chr21:39517261-39519776~~chr21:39714731-39716796,
chr21:39517288-39519777~~chr21:39715026-39717283,
chr21:39517297-39519497~~chr21:39714676-39716787,
chr21:39517303-39519751~~chr21:39705185-39706929,
chr21:39517303-39519751~~chr21:39712480-39713816,
chr21:39517303-39519751~~chr21:39715020-39717112,
chr21:39517308-39519721~~chr21:39714941-39716803,
chr21:39517315-39519547~~chr21:39714729-39716798,
chr21:39517322-39519410~~chr21:39715065-39716809,
chr21:39517329-39519377~~chr21:39715066-39716784,
chr21:39517336-39519705~~chr21:39715042-39717340,
chr21:39517343-39519431~~chr21:39715064-39716775,
chr21:39517353-39519456~~chr21:39715029-39716810,
chr21:39517354-39519438~~chr21:39705387-39706980,
chr21:39517354-39519438~~chr21:39712470-39713909,
chr21:39517354-39519438~~chr21:39715117-39716791,
chr21:39517358-39519642~~chr21:39705371-39706965,
chr21:39517358-39519642~~chr21:39714870-39717016,
chr21:39517360-39519534~~chr21:39705354-39706952,
chr21:39517360-39519534~~chr21:39712511-39713822,
chr21:39517360-39519534~~chr21:39715036-39716800,
chr21:39517368-39519427~~chr21:39715102-39716748,
chr21:39517369-39519405~~chr21:39715081-39716789,
chr21:39517370-39519432~~chr21:39715121-39716751,
chr21:39517370-39519511~~chr21:39715052-39716779,
chr21:39517372-39519496~~chr21:39715100-39716804,
chr21:39517377-39519678~~chr21:39715115-39716829,
chr21:39517379-39519777~~chr21:39714973-39716797,
chr21:39517380-39519751~~chr21:39714950-39717021,
chr21:39517407-39519894~~chr21:39705344-39706807,
chr21:39517407-39519894~~chr21:39715098-39716781,
chr21:39517409-39519453~~chr21:39715079-39716803,
chr21:39517410-39519337~~chr21:39715310-39716764,
chr21:39517417-39519653~~chr21:39715029-39716795,
chr21:39517439-39519408~~chr21:39715248-39716850,
chr21:39517449-39519764~~chr21:39714705-39716820,
chr21:39517500-39519305~~chr21:39715098-39716750,
chr21:39517500-39519881~~chr21:39715027-39716807,
chr21:39517539-39519419~~chr21:39714972-39716820,
chr21:39517541-39519337~~chr21:39715220-39716785,
chr21:39517544-39519746~~chr21:39705156-39706958,
chr21:39517544-39519746~~chr21:39715029-39716799,
chr21:39517545-39519545~~chr21:39715058-39716803,
chr21:39517560-39519419~~chr21:39715031-39716746,
chr21:39517570-39519399~~chr21:39715260-39716808,
chr21:39517583-39519436~~chr21:39715151-39716788,
chr21:39517618-39519383~~chr21:39715097-39716777,
chr21:39517656-39519379~~chr21:39715099-39716759,
chr21:39517703-39519567~~chr21:39715099-39716856,
chr21:39517712-39519561~~chr21:39715048-39716830,
chr21:39517734-39519372~~chr21:39715080-39716802,
chr21:39517800-39519427~~chr21:39715053-39716761,
chr21:39517814-39519374~~chr21:39715017-39716720,
chr21:39517826-39519509~~chr21:39714989-39716693,
chr21:39517837-39519461~~chr21:39715046-39716689,
chr21:39517839-39519351~~chr21:39714993-39716666,
chr21:39517856-39519435~~chr21:39714989-39716725,
chr21:39517859-39519254~~chr21:39715322-39716629,
chr21:39517864-39519219~~chr21:39715357-39716651,
chr21:39525000-39550000~~chr21:39700000-39725000,
chr21:39550000-39575000~~chr21:39700000-39725000,
chr21:39600000-39625000~~chr21:39700000-39725000,
chr21:39633375-39634630~~chr21:39715081-39716789,
chr21:39700000-39725000~~chr21:41425000-41450000,