- Basic information
- CohesinDB ID: CDBP00419589
- Locus: chr21-39723416-39724008
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Data sourse: GSE206145-GSE177045
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
69% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 62%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, ZFX, XBP1, FOXA1, ZNF205, RELA, CREBBP, GATA3, NRIP1, MED1, NR3C1, NCOA3, NR2F2, ZNF217, ESR1, GRHL2, TFAP2A, PAX3-FOXO1, AR, HDAC2, E2F1, NCOA2
- Target gene symbol (double-evidenced CRMs): BRWD1,LCA5L,PSMG1,MX1,GET1,SH3BGR,B3GALT5,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000183527,
ENSG00000185658,
ENSG00000285815,
ENSG00000182093,
ENSG00000157578,
ENSG00000185437,
ENSG00000183778,
ENSG00000157601,
- Related loop:
chr21:39100000-39125000~~chr21:39700000-39725000,
chr21:39150000-39175000~~chr21:39700000-39725000,
chr21:39225000-39250000~~chr21:39700000-39725000,
chr21:39300000-39325000~~chr21:39700000-39725000,
chr21:39400000-39425000~~chr21:39700000-39725000,
chr21:39500000-39525000~~chr21:39700000-39725000,
chr21:39517168-39519542~~chr21:39725249-39727184,
chr21:39517449-39519764~~chr21:39725321-39727028,
chr21:39525000-39550000~~chr21:39700000-39725000,
chr21:39550000-39575000~~chr21:39700000-39725000,
chr21:39600000-39625000~~chr21:39700000-39725000,
chr21:39700000-39725000~~chr21:41425000-41450000,