- Basic information
- CohesinDB ID: CDBP00419594
- Locus: chr21-39750744-39751143
-
Data sourse: GSE25021, GSE86191, GSE206145-GSE177045
-
Cell type: MCF-7, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 81%,
"14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, POU2F2, CBX1, MYCN, NKX2-2, TOP2A, SOX2, ZFX, XBP1, ZBTB48, WT1, STAT1, ZNF205, TET2, YY1, RELA, CREBBP, ATF3, MYC, AHR, GR, SP140, NKX2-1, TAL1, STAT3, NRIP1, NR3C1, ESRRA, PDX1, NCOA3, NR2F1, SNAI2, EZH2, ESR1, OCA2, NCOA1, GRHL2, CTCF, AR, ZNF257, FLI1, NOTCH3, BRD4, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): PCP4,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops