- Basic information
- CohesinDB ID: CDBP00419595
- Locus: chr21-39762944-39764842
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Data sourse: ENCSR703TNG, GSE206145-GSE177045, GSE67783, GSE72082
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, PGR, CHD8, CBX1, PPARG, BRD3, ZNF263, POU5F1, SIN3A, ZFX, CTBP1, MYCN, XBP1, ZBTB48, WT1, SMAD3, FOXA1, DUX4, STAT1, MLL4, KDM4C, ERG, YY1, RELA, CREBBP, RARA, ZNF90, MYC, NFIC, SMARCA4, SP140, ARNT, HIF1A, ZIC2, ZNF444, NKX2-1, GATA3, SMC3, PRDM9, TAL1, STAT3, TOP2A, NRIP1, ZNF143, CDK8, FOS, GATA1, CBX2, NR3C1, ESRRA, CEBPB, NCOA3, NR2F2, TEAD1, TFAP2C, NR2F1, ETV1, EZH2, KDM5B, ESR1, TP53, GRHL2, CTCF, BRD2, JUN, ARRB1, TFAP2A, BCL11A, SPI1, AR, GATA2, GATAD2B, ZNF366, ASH2L, NOTCH3, BRD4, MAZ, NCOA2, AHR
- Target gene symbol (double-evidenced CRMs): PCP4,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 17
- Number of somatic mutations (non-coding): 0
- Related genes and loops