- Basic information
- CohesinDB ID: CDBP00419597
- Locus: chr21-39776876-39777010
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Data sourse: ENCSR000BTQ, GSE72082
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 83%,
"14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, BRD3, TOP2A, ZFX, SMAD3, FOXA1, ERG, RELA, GRHL3, ARNT, RXRA, GATA3, PRDM9, TAL1, NR2F2, ETV1, EZH2, NCOA1, SETDB1, CTCF, JUN, SP1, SPI1, AR, GATA2, AHR
- Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR,PCP4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183036,
- Related loop:
chr21:39500000-39525000~~chr21:39775000-39800000,
chr21:39650000-39675000~~chr21:39750000-39775000,
chr21:39750000-39775000~~chr21:39900000-39925000,
chr21:39750000-39775000~~chr21:40525000-40550000,
chr21:39750000-39775000~~chr21:40625000-40650000,
chr21:39750000-39775000~~chr21:41700000-41725000,
chr21:39775000-39800000~~chr21:39900000-39925000,
chr21:39775000-39800000~~chr21:40000000-40025000,
chr21:39775000-39800000~~chr21:40075000-40100000,
chr21:39775000-39800000~~chr21:40100000-40125000,
chr21:39775000-39800000~~chr21:40125000-40150000,
chr21:39775000-39800000~~chr21:40375000-40400000,