- Basic information
- CohesinDB ID: CDBP00419598
- Locus: chr21-39787003-39790494
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Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE67783, GSE86191, GSE36578, GSE101921, ENCSR806UKK, GSE51234, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, GSE105004, ENCSR676MJK, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE38411, GSE104888, GSE132649, GSE103477, GSE108869, GSE143937, GSE138405, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990
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Cell type: MDM, RH4, SLK, CVB-hiPSC, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, HeLa-S3, IMR-90, BCBL-1, K-562, DKO, H1-hESC, MB157, TC-71, GM2588, GBM39, HUES9, SK-N-SH, RT-112, CNCCs-H9ESC, HeLa-Tet-On, THP-1, HUES64, MCF-7, T-47D, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HeLa, CNCC-WT33iPSC, BGO3, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 60% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.433
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 59%,
"7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXA1, FOXA2
- Target gene symbol (double-evidenced CRMs): PCP4,GET1-SH3BGR,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 41
- Number of somatic mutations (non-coding): 41
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183036,
- Related loop:
chr21:39500000-39525000~~chr21:39775000-39800000,
chr21:39517303-39519751~~chr21:39787215-39789565,
chr21:39775000-39800000~~chr21:39900000-39925000,
chr21:39775000-39800000~~chr21:40000000-40025000,
chr21:39775000-39800000~~chr21:40075000-40100000,
chr21:39775000-39800000~~chr21:40100000-40125000,
chr21:39775000-39800000~~chr21:40125000-40150000,
chr21:39775000-39800000~~chr21:40375000-40400000,
chr21:39787215-39789565~~chr21:39910588-39912275,
chr21:39787215-39789565~~chr21:40120093-40122096,
chr21:39787253-39789571~~chr21:39855456-39856836,
chr21:39787253-39789571~~chr21:39866317-39868146,
chr21:39787253-39789571~~chr21:39910500-39912317,
chr21:39787253-39789571~~chr21:40120165-40122042,
chr21:39787296-39789560~~chr21:39910501-39912411,
chr21:39787299-39789416~~chr21:40120132-40122088,
chr21:39787325-39789860~~chr21:40119606-40122062,
chr21:39787329-39789539~~chr21:40119863-40122093,
chr21:39787332-39789505~~chr21:39910608-39912279,
chr21:39787332-39789505~~chr21:40120236-40122026,
chr21:39787336-39789600~~chr21:40119842-40122098,
chr21:39787340-39789791~~chr21:40120108-40122096,
chr21:39787452-39789550~~chr21:40119861-40122095,
chr21:39787515-39789551~~chr21:40120098-40121959,
chr21:39787550-39789577~~chr21:40119552-40122087,
chr21:39787674-39789450~~chr21:40120405-40121950,
chr21:39787674-39789450~~chr21:40385781-40387172,
chr21:39787686-39789383~~chr21:40120169-40122003,
chr21:39787697-39789341~~chr21:40120354-40121926,
chr21:39787701-39789371~~chr21:40120284-40121931,
chr21:39787705-39789776~~chr21:39910608-39912422,
chr21:39787705-39789776~~chr21:40120273-40121717,
chr21:39787706-39789391~~chr21:40120171-40121990,
chr21:39787712-39789349~~chr21:40120365-40121817,
chr21:39787716-39789399~~chr21:40120443-40121742,
chr21:39787717-39789400~~chr21:40120433-40122067,
chr21:39787718-39789326~~chr21:40120460-40121701,
chr21:39787723-39789945~~chr21:40120221-40121922,
chr21:39787733-39789380~~chr21:40120291-40121826,
chr21:39787751-39789240~~chr21:40120130-40122082,
chr21:39787773-39789310~~chr21:40120389-40121831,