- Basic information
- CohesinDB ID: CDBP00419600
- Locus: chr21-39796085-39796993
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Data sourse: GSE67783, GSE111913, ENCSR404BPV, GSE86191
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Cell type: Neurons-H1, RT-112, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 68%,
"9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZNF283, CBFA2T2, CHD8, FOXA2, NKX2-2, ZFX, WT1, ZBTB48, STAT1, FOXA1, ZSCAN5A, TET2, DDX5, HOXB13, ERG, YY1, RELA, TFAP4, ATF3, MYC, SP140, ARNT, HIF1A, GRHL3, ATF4, NKX2-1, GATA3, ATF2, HMBOX1, GABPA, APC, MAX, ZNF10, PRDM14, ZNF143, NKX3-1, MED1, TLE3, NR3C1, CEBPB, TRIM28, SCRT2, CREB1, ETV1, EZH2, PIAS1, ESR1, ZNF334, CTCF, T, BCL11A, SPI1, BAF155, AR, GATA2, ARID1A, IRF4, ATF7, ASH2L, HNRNPLL, SCRT1, MAZ, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): PCP4,SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183036,
- Related loop:
chr21:39500000-39525000~~chr21:39775000-39800000,
chr21:39775000-39800000~~chr21:39900000-39925000,
chr21:39775000-39800000~~chr21:40000000-40025000,
chr21:39775000-39800000~~chr21:40075000-40100000,
chr21:39775000-39800000~~chr21:40100000-40125000,
chr21:39775000-39800000~~chr21:40125000-40150000,
chr21:39775000-39800000~~chr21:40375000-40400000,