- Basic information
- CohesinDB ID: CDBP00419615
- Locus: chr21-39853210-39853546
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Data sourse: ENCSR000BTQ, GSE72082, GSE83726
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Cell type: MCF-7, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 74%,
"9_Het": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, FOSL1, PGR, NME2, FOXA1, TFAP4, PRDM1, SMARCE1, ZSCAN4, TP63, ZNF736, MYOG, TEAD1, TRIM28, ELF1, ZNF217, ESR1, OCA2, JUN, CTCF, BAF155, MNT, DPF2, E2F1, ZNF175, PDX1, TFAP2C, GLIS1, POU2F2, CHD8, NANOG, ZSCAN5D, MYCN, ZNF263, ZNF778, CTBP1, ZBTB17, DUX4, ZBTB48, STAT1, DDX5, ERG, ASCL1, ONECUT1, MYC, RFX1, RAD21, GRHL3, NKX2-1, STAT3, NKX3-1, TERF2, NR3C1, CEBPB, ESRRA, CREB1, EZH2, GRHL2, HDAC2, GATA2, GATAD2B, NCOA2, RUNX1, CBX1, NKX2-2, EZH2phosphoT487, SIN3A, ZFX, SMAD3, TET2, CREBBP, ZXDC, ZNF384, PRDM9, ETV6, MAFB, CHD1, FOS, MED1, SCRT2, PIAS1, SETDB1, MAFK, TFAP2A, POU2F3, CTBP2, SMC3, NCOR2, STAG1, CBFA2T2, FOXA2, SS18, WT1, FOXF1, YY2, HOXB13, YY1, RELA, SP140, HIF1A, GATA3, MAX, NRIP1, ZSCAN26, ZNF143, TLE3, ZNF592, NCOA3, NR2F2, TCF7L2, NR2F1, ZNF687, ZBTB6, TP53, PKNOX1, ZNF334, MYOD1, T, BRD2, AR, PAX3-FOXO1, ZNF579, BRD4, SCRT1, JUND, MAZ, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,B3GALT5,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183778,
- Related loop:
chr21:38850000-38875000~~chr21:39850000-39875000,
chr21:39500000-39525000~~chr21:39850000-39875000,
chr21:39600000-39625000~~chr21:39850000-39875000,
chr21:39787253-39789571~~chr21:39855456-39856836,
chr21:39850000-39875000~~chr21:40050000-40075000,
chr21:39850000-39875000~~chr21:40100000-40125000,
chr21:39850000-39875000~~chr21:40125000-40150000,
chr21:39850000-39875000~~chr21:40275000-40300000,
chr21:39850000-39875000~~chr21:40375000-40400000,