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Basic information

CohesinDB ID: CDBP00419618

Locus: chr21-39863160-39864324

Data sourse: ENCSR000BTQ, ENCSR000BTU, GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE83726, ENCSR703TNG, GSE25021

Cell type: MCF-7, RH4, HCT-116, Ishikawa, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: Mau2,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 48% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, POU2F2, SMC1A, CBX1, PGR, POU5F1, MYCN, NKX2-2, SIN3A, ZFX, TEAD4, XBP1, FOXA2, ZBTB48, WT1, SMAD3, FOXA1, MLL4, HOXB13, TFAP4, ERG, RELA, CREBBP, ZNF384, ASCL1, NEUROD1, ATF3, MYC, NFIC, RAD21, SP140, GRHL3, ARNT, NFIB, HIF1A, OTX2, NKX2-1, PROX1, GATA3, STAT3, ETV6, MAX, NKX3-1, GATA1, ZNF143, NRIP1, CRY1, MED1, CDX2, NR3C1, CEBPB, ESRRA, TEAD1, NR2F2, SCRT2, KLF6, TFAP2C, EZH2, PIAS1, TP53, ESR1, OCA2, ZNF334, SETDB1, CTCF, ELF3, TCF12, EP300, JUN, GSPT2, HNF4A, MAFK, ZNF579, GATA2, POU2F3, ZNF263, BRD4, PHIP, NR5A2, HCFC1R1, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): SH3BGR,PCP4,GET1-SH3BGR,B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 9

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000183036,

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Deatailed information for cohesin site CDBP00419618