Browse_each

Basic information

CohesinDB ID: CDBP00419620

Locus: chr21-39869137-39870155

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, GSE83726

Cell type: MCF-7, RPE, Fibroblast, RH4, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 48% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 46%, "14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, PGR, SOX2, XBP1, FOXA1, SUZ12, PBX2, ATF3, ZC3H8, NFIC, CTCFL, ZNF444, MECOM, JMJD1C, TEAD1, ZNF121, SNAI2, ZNF217, ESR1, OCA2, CTCF, BAF155, PAX8, IRF4, PRKDC, E2F1, SMC1, ZNF350, TEAD4, GTF2F1, PDX1, TFAP2C, GLIS1, POU2F2, CHD8, ZNF425, MYCN, POU5F1, RUNX1T1, ZBTB17, ZBTB48, ZSCAN5A, STAT1, DUX4, SRF, TBP, ERG, ASCL1, OGG1, MYC, SMARCA4, KDM4A, RAD21, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, RCOR1, NFE2, MIER3, NR3C1, CEBPB, CREB1, EZH2, GRHL2, SPI1, HDAC2, GATA2, MXD3, HCFC1R1, RUNX1, AHRR, SMC1A, CBX1, BCL6, EZH2phosphoT487, NKX2-2, SIN3A, ZFX, SMAD3, ZNF654, TET2, TRIM22, ZBTB2, ZNF384, ZNF35, CREBBP, NFYC, ARNT, ATF2, PRDM9, SMAD4, FOS, HMGXB4, MED1, TEAD3, ZEB1, MYB, PIAS1, SMAD1, KLF9, SETDB1, USF1, IKZF5, REST, ZBTB7A, POU2F3, ASH2L, HNRNPLL, BCOR, FOXP1, SMC3, STAG2, STAG1, PAX7, TRP47, CBFA2T2, ZNF283, TBL1X, FOXA2, CREM, EBF1, WT1, CDK9, HOXB13, YY1, RELA, NEUROD1, SP140, ZFP36, HIF1A, OTX2, GATA3, MAX, ZNF143, NCOA3, NR2F1, TCF7L2, KDM5B, TP53, PKNOX1, ZNF687, ZNF334, ZSCAN22, MYOD1, BRD2, KAT8, AR, TAF1, EGLN2, HEXIM1, RB1, HSF1, ZBTB26, NOTCH3, BRD4, SCRT1, MAZ

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,SH3BGR,B3GALT5,PCP4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000183036,

eachgene

Deatailed information for cohesin site CDBP00419620