- Basic information
- CohesinDB ID: CDBP00419624
- Locus: chr21-39884258-39884729
-
Data sourse: GSE206145-NatGen2015, GSE67783
-
Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, GLIS1, AGO1, TRP47, POU2F2, CHD8, TBL1X, EZH2phosphoT487, EBF1, NKX2-2, SOX2, ZFX, RBPJ, MYCN, XBP1, ZBTB48, SMAD3, WT1, KDM4C, NFKBIA, TET2, ZBTB33, PAX6, KDM1A, ERG, YY1, PBX1, ASCL1, OGG1, RELA, RUNX2, MYC, SMARCA4, CDK6, SP140, NRF1, HIF1A, GRHL3, POU5F1, GATA3, SMC3, GABPA, STAT3, MAX, TOP2A, NKX3-1, GATA1, HAND2, NR3C1, NCOA3, KMT2A, NR2F1, EZH2, STAG1, ESR1, OCA2, KLF9, PITX3, MED, SETDB1, CTCF, ARRB1, GSPT2, AR, PTBP1, POU2F3, FLI1, HSF1, BRD4, TCF3, MAZ, HCFC1R1, TEAD4, PDX1, TFAP2C
- Target gene symbol (double-evidenced CRMs): PCP4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops