- Basic information
- CohesinDB ID: CDBP00419633
- Locus: chr21-39919712-39920331
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Data sourse: GSE120943, GSE67783, GSE72082, GSE98367
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Cell type: MCF-7, Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 60%,
"9_Het": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: LCORL, ZNF621, NME2, XBP1, FOXA1, SUZ12, ZFHX2, ZBTB7B, HDGF, TSC22D4, BMI1, NFIC, ATF3, ZBTB5, ZNF444, SMARCE1, MITF, ZNF736, CDC5L, TEAD1, BCLAF1, ESR1, OCA2, CTCF, TCF12, E4F1, MNT, GATA6, DPF2, PAX8, TRIM24, ZNF410, ZNF512B, ZNF776, ZNF280A, EHMT2, PDX1, YBX1, POU2F2, CHD8, BRD1, NANOG, MYCN, ZNF239, POU5F1, KDM4C, CTBP1, ZBTB1, MTA2, ZBTB48, ZSCAN5A, ASH1L, NONO, SRF, DDX5, NBN, ARID3A, ERG2, ZNF114, OGG1, MCM5, MYC, SMARCA4, RFX1, FOXK2, ZNF8, STAT3, IKZF1, RCOR1, ZNF639, NFRKB, ESRRA, CREB1, YBX3, EZH2, ARHGAP35, HES1, ZNF202, IRF1, HDAC2, SSRP1, ZNF644, GATAD2B, ATM, SMARCA5, SALL2, HDAC1, ZNF707, ZFX, ZNF534, ZNF473, TBX3, NFXL1, ERG3, TRIM22, NFIB, ARNT, SOX11, SNIP1, ATF2, SETDB1, SP1, ARID2, ATF7, AFF1, BCOR, FOXP1, MLLT1, NCOA4, ZNF207, MTA3, FOXA2, CREM, WT1, ZNF662, ZBTB33, ZKSCAN1, RELA, TARDBP, NEUROD1, ZNF148, ZNF521, ZNF282, SP140, ZNF311, ZSCAN26, ZNF143, ZNF592, NCOA3, ZNF544, ZNF791, KDM5B, ZNF687, PKNOX1, BCL6B, EGR2, EGR1, HSF1, BRD4, ZNF248, ZNF24
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,B3GALT5,PCP4,MX1,SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183778,
ENSG00000183036,
ENSG00000157601,
- Related loop:
chr21:39500000-39525000~~chr21:39900000-39925000,
chr21:39500000-39525000~~chr21:39925000-39950000,
chr21:39600000-39625000~~chr21:39900000-39925000,
chr21:39750000-39775000~~chr21:39900000-39925000,
chr21:39775000-39800000~~chr21:39900000-39925000,
chr21:39900000-39925000~~chr21:40100000-40125000,
chr21:39900000-39925000~~chr21:40375000-40400000,
chr21:39900000-39925000~~chr21:41425000-41450000,