- Basic information
- CohesinDB ID: CDBP00419636
- Locus: chr21-39925600-39925902
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
48% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 74%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, CBX1, FOXA2, MYCN, NKX2-2, CREM, EZH2phosphoT487, ZFX, TOP2A, WT1, ZBTB48, TET2, CDK9, KDM1A, YY1, RELA, ATF3, MYC, SMARCA4, RAD21, SP140, ARNT, GRHL3, ATF2, PRDM9, MAX, TP63, CHD1, ZNF143, DNMT3B, MED1, CREB1, EZH2, ESR1, KLF9, L3MBTL2, ZNF334, SETDB1, JUN, BRD2, CTCF, PAX8, REST, IRF4, ATF7, ASH2L, BRD4, SCRT1, JUND, MAZ, SMC3, ATF1, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SH3BGR,PCP4,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183036,
- Related loop:
chr21:39500000-39525000~~chr21:39900000-39925000,
chr21:39500000-39525000~~chr21:39925000-39950000,
chr21:39600000-39625000~~chr21:39900000-39925000,
chr21:39750000-39775000~~chr21:39900000-39925000,
chr21:39775000-39800000~~chr21:39900000-39925000,
chr21:39900000-39925000~~chr21:40100000-40125000,
chr21:39900000-39925000~~chr21:40375000-40400000,
chr21:39900000-39925000~~chr21:41425000-41450000,