- Basic information
- CohesinDB ID: CDBP00419657
- Locus: chr21-40042249-40045555
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE25021, GSE115602, ENCSR000BTU, GSE67783, GSE86191, GSE138405, GSE76893, GSE51234, GSE206145-NatGen2015, ENCSR703TNG, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE68388, GSE126990
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Cell type: MCF-7, H1-hESC, Fibroblast, HCT-116, Hela-Kyoto, THP-1, Ishikawa, HUES64, SK-N-SH, GP5d, HSPC, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 64%,
"9_Het": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, SMC1A, CBX1, FOXA2, MYCN, POU5F1, ZFX, XBP1, ZBTB48, WT1, FOXA1, TET2, ERG3, ERG2, HOXB13, ZBTB21, YY1, RELA, TAF15, MYC, RAD21, SP140, HIF1A, SOX11, ATF2, NRIP1, ZNF143, ESRRA, CREB1, NR2F1, KDM5B, ESR1, OCA2, SETDB1, JUN, CTCF, SPI1, GSPT2, AR, EGLN2, ATF7, NOTCH3, JUND, BRD4, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: Non-small_cell_lung_cancer_(survival)
- Number of somatic mutations (coding): 490
- Number of somatic mutations (non-coding): 0
- Related genes and loops