- Basic information
- CohesinDB ID: CDBP00419659
- Locus: chr21-40049939-40050260
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Data sourse: ENCSR000BLD, GSE111913, GSE105028, ENCSR000ECE, GSE97394
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Cell type: RT-112, H1-hESC, HUES64, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 48%,
"7_Enh": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, FOXA1, NFIC, CHD7, ZNF629, ETV1, SNAI2, ESR1, PITX3, CTCF, JUN, BAF155, RFX5, ZNF528, TEAD4, PDX1, RBPJ, TFAP2C, NANOG, CHD8, BRD3, CTBP1, ZBTB17, STAT1, ERG, ZBTB21, ASCL1, ZNF341, MYC, RAD21, PROX1, NKX2-1, NKX3-1, NR3C1, ESRRA, CEBPB, CREB1, EZH2, GRHL2, SPI1, HDAC2, GATA2, SIX2, ZNF554, RUNX1, NKX2-2, ZFX, SMAD3, ZFP37, CREBBP, ZNF184, ATF2, FOXM1, MAFB, FOS, MED1, PIAS1, KLF9, SETDB1, USF1, BCL11A, REST, ATF7, ASH2L, FOXP1, FOXA2, EBF1, ZNF600, ZSCAN16, FOXF1, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, ZIC2, HIF1A, OTX2, MAX, TLE3, TP53, ZNF334, MYOD1, BRD2, AR, PAX3-FOXO1, ZNF366, BRD4, JUND, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,PCP4,SH3BGR,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops