- Basic information
- CohesinDB ID: CDBP00419663
- Locus: chr21-40059857-40060679
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Data sourse: GSE206145-NatGen2015, ENCSR198ZYJ, ENCSR404BPV
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Cell type: Neurons-H1, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 75%,
"14_ReprPCWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, NKX2-2, EZH2phosphoT487, ZFX, XBP1, FOXA1, HOXB13, ASCL1, OGG1, ZNF341, MYC, SMARCA4, SP140, GRHL3, ARNT, MAFB, NKX3-1, MITF, MED1, NR3C1, ZEB1, NCOA3, SCRT2, EZH2, ESR1, SPI1, BCL11A, PAX3-FOXO1, AR, PAX8, REST, ASH2L, BRD4, SCRT1, FOXP1, PDX1, AHR
- Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,SH3BGR,PCP4,B3GALT5
- Function elements
- Human SNPs: Body_mass_index
- Number of somatic mutations (coding): 28
- Number of somatic mutations (non-coding): 0
- Related genes and loops