- Basic information
- CohesinDB ID: CDBP00419667
- Locus: chr21-40074363-40075414
-
Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR703TNG, GSE115602
-
Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL,Rad21,Mau2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 68%,
"5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, PGR, CBX1, CHD8, POU5F1, MYCN, SIN3A, ZFX, ZBTB48, WT1, FOXA1, TET2, ERG3, YY1, RELA, CREBBP, ZXDC, AHR, MYC, GATA4, ARNT, HIF1A, GATA3, SMARCE1, ETV6, NRIP1, ZNF143, MED1, TEAD1, NR2F1, KDM5B, ESR1, PKNOX1, GRHL2, TBX5, SETDB1, CTCF, EP300, MNT, AR, DPF2, YAP1, EGLN2, CTBP2, BRD4, MBD2, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): B3GALT5,PCP4,SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 196
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183778,
ENSG00000183036,
- Related loop:
chr21:39500000-39525000~~chr21:40050000-40075000,
chr21:39525000-39550000~~chr21:40075000-40100000,
chr21:39600000-39625000~~chr21:40050000-40075000,
chr21:39600000-39625000~~chr21:40075000-40100000,
chr21:39775000-39800000~~chr21:40075000-40100000,
chr21:39850000-39875000~~chr21:40050000-40075000,
chr21:39975000-40000000~~chr21:40075000-40100000,
chr21:40075000-40100000~~chr21:40300000-40325000,