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Basic information

CohesinDB ID: CDBP00419677

Locus: chr21-40133778-40134486

Data sourse: GSE131606, GSE67783, GSE86191

Cell type: HCT-116, HSPC, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 60%, "9_Het": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX1, MYCN, ZNF263, ZFX, ZNF600, WT1, ZBTB48, ZSCAN5A, FOXA1, CREBBP, MYC, SP140, ARNT, MAX, MITF, NFE2, PLAG1, EZH2, ESR1, USF2, CTCF, USF1, BCL11A, HSF1, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): GET1-SH3BGR,SH3BGR,TMPRSS2,PCP4,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 102

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183036, ENSG00000157601, ENSG00000184012,

eachgene

Deatailed information for cohesin site CDBP00419677