- Basic information
- CohesinDB ID: CDBP00419682
- Locus: chr21-40149386-40149804
-
Data sourse: ENCSR703TNG, ENCSR153HNT, GSE72082
-
Cell type: K-562, MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: False
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 76%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: YBX1, EHMT2, POU2F2, ZNF195, BRD1, ZNF207, HDAC1, FOXA2, MTA3, ZNF621, ZFX, CTBP1, ZBTB1, FOXA1, NONO, ZNF662, ZNF473, SUZ12, ZBTB33, MCM2, TRIM22, PHB2, ZKSCAN1, ARID3A, ZBTB7B, ZNF114, RELA, CREBBP, TARDBP, HDGF, NEUROD1, BMI1, MYC, MCM5, ZNF148, RFX1, ZNF521, MCM3, PRDM1, ARNT, ZNF444, NFIB, BRCA1, ZNF311, FOXK2, PAX5, ZNF398, ZNF639, ESRRA, ZNF592, NCOA3, BCLAF1, DDX5, CREB1, ZNF544, ZNF687, PKNOX1, SETDB1, BCL6B, ZIK1, PLRG1, SP1, HES1, AR, DPF2, HDAC2, ZBTB40, GATAD2B, ATF7, ATM, ZNF512B, ZNF776, ZNF24, SALL2
- Target gene symbol (double-evidenced CRMs): TMPRSS2,SH3BGR,MX1,PCP4,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 48
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183036,
ENSG00000157601,
ENSG00000184012,
- Related loop:
chr21:31250000-31275000~~chr21:40150000-40175000,
chr21:39500000-39525000~~chr21:40125000-40150000,
chr21:39525000-39550000~~chr21:40125000-40150000,
chr21:39775000-39800000~~chr21:40125000-40150000,
chr21:39850000-39875000~~chr21:40125000-40150000,
chr21:40125000-40150000~~chr21:40225000-40250000,
chr21:40125000-40150000~~chr21:40300000-40325000,
chr21:40125000-40150000~~chr21:40325000-40350000,
chr21:40125000-40150000~~chr21:40375000-40400000,
chr21:40125000-40150000~~chr21:40400000-40425000,
chr21:40125000-40150000~~chr21:40425000-40450000,
chr21:40125000-40150000~~chr21:40500000-40525000,
chr21:40125000-40150000~~chr21:40625000-40650000,
chr21:40125000-40150000~~chr21:40675000-40700000,
chr21:40125000-40150000~~chr21:40700000-40725000,
chr21:40125000-40150000~~chr21:40825000-40850000,
chr21:40125000-40150000~~chr21:40900000-40925000,
chr21:40125000-40150000~~chr21:41000000-41025000,
chr21:40125000-40150000~~chr21:41025000-41050000,
chr21:40125000-40150000~~chr21:41050000-41075000,
chr21:40125000-40150000~~chr21:41075000-41100000,
chr21:40125000-40150000~~chr21:41125000-41150000,
chr21:40125000-40150000~~chr21:41450000-41475000,
chr21:40142884-40144840~~chr21:41045200-41046358,
chr21:40142884-40144840~~chr21:41068233-41070192,
chr21:40143196-40145254~~chr21:40841232-40842970,
chr21:40143203-40144858~~chr21:41068086-41070092,
chr21:40143203-40144858~~chr21:41133242-41135103,
chr21:40143203-40145143~~chr21:40385550-40387260,
chr21:40143209-40145089~~chr21:40385777-40387210,
chr21:40143209-40145089~~chr21:41068098-41070028,
chr21:40143211-40145650~~chr21:41070818-41072228,
chr21:40143216-40145182~~chr21:40385497-40387239,
chr21:40143216-40145182~~chr21:41068067-41070302,
chr21:40143218-40145094~~chr21:40385505-40387214,
chr21:40143218-40145094~~chr21:41068097-41070414,
chr21:40143218-40145094~~chr21:41133240-41135091,
chr21:40143220-40145191~~chr21:41045017-41046620,
chr21:40143220-40145191~~chr21:41068083-41070648,
chr21:40143220-40145193~~chr21:40385428-40387263,
chr21:40143223-40145165~~chr21:40385500-40387251,
chr21:40143223-40145165~~chr21:41068145-41070397,
chr21:40143235-40145160~~chr21:40385101-40387258,
chr21:40143235-40145160~~chr21:40841024-40843128,
chr21:40143235-40145160~~chr21:41068042-41070202,
chr21:40143236-40145155~~chr21:40385794-40387196,
chr21:40143238-40145160~~chr21:41068059-41070286,
chr21:40143238-40145160~~chr21:41133234-41134735,
chr21:40143239-40145147~~chr21:41068073-41070024,
chr21:40143249-40145199~~chr21:41068260-41070064,
chr21:40143254-40145149~~chr21:40385829-40387199,
chr21:40143256-40145192~~chr21:40385428-40387257,
chr21:40143258-40145166~~chr21:40385841-40387219,
chr21:40143262-40144895~~chr21:41068445-41069912,
chr21:40143263-40145135~~chr21:40385795-40387254,
chr21:40143263-40145135~~chr21:40841259-40842961,
chr21:40143263-40145135~~chr21:41068059-41070218,
chr21:40143267-40144892~~chr21:41068032-41070376,
chr21:40143267-40144892~~chr21:41133281-41134757,
chr21:40143268-40144900~~chr21:40385471-40387249,
chr21:40143268-40144900~~chr21:41042582-41043894,
chr21:40143268-40144900~~chr21:41068052-41070078,
chr21:40143268-40144900~~chr21:41133210-41134770,
chr21:40143275-40144996~~chr21:41070881-41072256,
chr21:40143276-40145164~~chr21:41068061-41070317,
chr21:40143283-40145087~~chr21:41068113-41070021,
chr21:40143283-40145087~~chr21:41121049-41122875,
chr21:40143283-40145087~~chr21:41133208-41135081,
chr21:40143286-40144881~~chr21:41133185-41134897,
chr21:40143287-40145205~~chr21:41068185-41070081,
chr21:40143288-40144975~~chr21:41068410-41069966,
chr21:40143291-40145135~~chr21:41068238-41070028,
chr21:40143292-40144823~~chr21:41068564-41069996,
chr21:40143311-40145530~~chr21:41068080-41070453,
chr21:40143311-40145530~~chr21:41133270-41135110,
chr21:40143361-40144725~~chr21:41068534-41069892,
chr21:40143361-40144725~~chr21:41133411-41134824,
chr21:40143368-40144757~~chr21:41068035-41070009,
chr21:40143375-40144769~~chr21:41068498-41069899,
chr21:40143375-40144769~~chr21:41133440-41134760,
chr21:40143385-40144715~~chr21:41133301-41134874,
chr21:40143385-40144767~~chr21:41133283-41134768,
chr21:40143388-40144776~~chr21:41068509-41069855,
chr21:40143388-40144776~~chr21:41133401-41134738,
chr21:40145591-40147301~~chr21:40385508-40387221,
chr21:40150000-40175000~~chr21:40275000-40300000,
chr21:40150000-40175000~~chr21:40375000-40400000,
chr21:40150000-40175000~~chr21:40400000-40425000,
chr21:40150000-40175000~~chr21:40425000-40450000,
chr21:40150000-40175000~~chr21:40775000-40800000,
chr21:40150000-40175000~~chr21:40825000-40850000,
chr21:40150000-40175000~~chr21:40900000-40925000,
chr21:40150000-40175000~~chr21:41000000-41025000,
chr21:40150000-40175000~~chr21:41025000-41050000,
chr21:40150000-40175000~~chr21:41050000-41075000,
chr21:40150000-40175000~~chr21:41075000-41100000,