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Basic information

CohesinDB ID: CDBP00419689

Locus: chr21-40165050-40166180

Data sourse: ENCSR198ZYJ, ENCSR404BPV

Cell type: Neurons-H1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 56%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NANOG, CHD8, CBX1, FOXA2, NKX2-2, SOX2, ZFX, POU4F2, CTBP1, SIN3A, SMAD3, FOXA1, TBP, KDM1A, RELA, CREBBP, ZNF384, AHR, BMI1, MYC, GATA4, RFX1, CHD7, RAD21, GRHL3, BACH1, HIF1A, GATA3, SMC3, MAX, NKX3-1, FOS, ZNF143, MED1, CEBPB, CREB1, STAG1, ZNF217, ZNF687, OCA2, KLF9, ESR1, TBX5, ZSCAN22, CTCF, JUN, MAFK, EP300, MNT, AR, DPF2, NKX2-5, REST, E2F6, HDAC2, GATA2, ATF7, ASH2L, BRD4, JUND, TEAD4, GTF2F1, PDX1, RBPJ

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 18

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419689