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Basic information

CohesinDB ID: CDBP00419691

Locus: chr21-40172995-40174525

Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE25021, GSE76893, ENCSR000BLY, ENCSR404BPV, GSE105028, ENCSR000ECE, GSE68388, GSE83726, ENCSR703TNG, GSE131606, GSE116344, GSE145327, GSE97394, GSE115602

Cell type: MCF-7, H1-hESC, RH4, Neurons-H1, DKO, H9-hESC, SK-N-SH, HuCC-T1, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 9% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SMC3,Rad21,SA1,SMC1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 66%, "14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, CBX1, TOP2A, ZFX, XBP1, SMAD3, STAT1, RAD21, PRDM1, ARNT, GRHL3, NKX2-1, MAX, MITF, MED1, PLAG1, CREB1, SMAD1, EZH2, ESR1, TP53, SETDB1, USF2, CTCF, USF1, AR, PAX3-FOXO1, JUND, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 18

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419691