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Basic information

CohesinDB ID: CDBP00419693

Locus: chr21-40176194-40177488

Data sourse: ENCSR000BLD, ENCSR000BLY, ENCSR404BPV, ENCSR000EHW, GSE105028, ENCSR000ECE, ENCSR000EHX, ENCSR198ZYJ, GSE83726, GSE97394

Cell type: H1-hESC, RH4, Neurons-H1, H9-hESC, SK-N-SH, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 57%, "14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CHD8, FOXA2, NKX2-2, EBF1, CHD2, RBPJ, ZFX, TEAD4, SOX2, MYCN, ZBTB48, WT1, FOXA1, TET2, CDK9, ERG, KDM1A, PBX1, ASCL1, MYC, NFIC, SMARCA4, RFX1, RAD21, CHD7, TCF4, SP140, HIF1A, GATA3, MAX, MAFB, NKX3-1, RCOR1, HAND2, MED1, NR3C1, MYOG, EZH2, SAP30, ESR1, KLF9, PITX3, SETDB1, EBF3, MYOD1, PHOX2B, CTCF, TCF12, USF1, EP300, PAX3-FOXO1, HDAC2, REST, GATA2, IRF4, BRD4, TCF3, SMC3, PDX1, AHR

Target gene symbol (double-evidenced CRMs): MX2,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 28

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183486, ENSG00000157601,

eachgene

Deatailed information for cohesin site CDBP00419693