- Basic information
- CohesinDB ID: CDBP00419695
- Locus: chr21-40182514-40183154
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Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE72082, GSE110061, GSE206145-NatGen2015, GSE115602
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Cell type: MCF-7, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 50%,
"9_Het": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ERG2, REST, CBX1, MYC, ZNF263, GATA2, ZFX, SP140, KDM5B, GRHL2, SETDB1, ERG3, EGR2, CTCF, SP2, YY1
- Target gene symbol (double-evidenced CRMs): MX2,MX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops