- Basic information
- CohesinDB ID: CDBP00419698
- Locus: chr21-40186622-40186984
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Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR404BPV, GSE86191
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Cell type: Neurons-H1, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 64%,
"9_Het": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, MAFG, CHD8, MYCN, ZNF263, NKX2-2, KDM4C, ZFX, ZBTB48, WT1, STAT1, ZSCAN5A, TET2, HOXB13, ZKSCAN1, ERG, YY1, RELA, OGG1, NEUROD1, ATF3, MYC, RAD21, SP140, GRHL3, HIF1A, OTX2, GATA3, PRDM9, STAT3, HNRNPH1, ZNF736, KLF5, NR2F2, ELF1, NCOA3, NR2F1, LMO2, ESR1, OCA2, C11orf30, SETDB1, MYOD1, ZNF652, CTCF, BRD2, MAFK, JUN, SP1, SPI1, GATA2, HSF1, SCRT1, CLOCK, AATF, SMC3, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): MX1,MX2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops