- Basic information
- CohesinDB ID: CDBP00419724
- Locus: chr21-40313272-40314811
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR000EHX, ENCSR703TNG, GSE25021
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Cell type: MCF-7, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SA1,Rad21,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 85%,
"9_Het": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, PGR, CBX1, BCL6, FOXA2, TOP2A, SIN3A, TEAD4, CTBP1, XBP1, GTF2B, FOXA1, SRF, BAHD1, HOXB13, RELA, CREBBP, ZXDC, MEN1, OGG1, NEUROD1, MYC, GR, RAD21, ARNT, HIF1A, OTX2, ATF2, GATA3, SMARCE1, FOXM1, ETV6, NRIP1, ZNF143, MED1, NR3C1, ZNF592, CEBPG, NCOA3, TEAD1, NR2F2, CEBPB, CREB1, NR2F1, TCF7L2, EZH2, ZNF217, ZNF687, ESR1, TFAP2C, NCOA1, GRHL2, PITX3, PKNOX1, TRPS1, PHOX2B, JUN, ZHX2, TCF12, NIPBL, EP300, CTCF, AR, GATA6, DPF2, HDAC2, YAP1, GATA2, REST, PAX8, ATF7, JUND, BRD4, CTBP2, CLOCK, MBD2, CUX1, SMARCA5, NCOA2, ELL2, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 0
- Related genes and loops