- Basic information
- CohesinDB ID: CDBP00419726
- Locus: chr21-40318353-40327457
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Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE76893, GSE105028, ENCSR000ECE, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, H1-hESC, HCT-116, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"9_Het": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, PGR, ZNF496, FOXA1, MEN1, WDHD1, DPF1, SMARCE1, TEAD1, ZNF217, ESR1, CTCF, TCF12, JUN, EP300, BAF155, MNT, DPF2, MED12, RAD51, PRKDC, ZNF512B, NR5A2, TEAD4, TFAP2C, CHD8, CTBP1, DUX4, UTX, SRF, ERG, RAD21, GABPA, NKX3-1, RCOR1, ZNF750, ESRRA, CEBPB, NR3C1, CREB1, GRHL2, TRPS1, ZHX2, ZSCAN2, KDM5A, HDAC2, GATA2, GATAD2B, SREBF1, SMARCA5, NCOA2, RUNX1, SMC1A, CBX1, SIN3A, NFXL1, ZXDC, ZNF384, CREBBP, GR, ARNT, NFIB, PRDM9, FOXM1, ETV6, CHD1, FOS, MED1, PML, ZMYM3, PIAS1, NCOA1, NIPBL, TFAP2A, REST, ARID1A, ATF7, CTBP2, MBD2, FOXP1, STAG1, MLLT1, ZNF283, FOXA2, MTA3, HOXB13, RELA, TARDBP, NEUROD1, HIF1A, GATA3, MAX, NRIP1, MTA1, TLE3, ZNF592, NCOA3, NR2F2, TCF7L2, NR2F1, ZNF687, TP53, AR, ZBTB40, YAP1, EGLN2, HSF1, BRD4, JUND, CLOCK, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 168
- Number of somatic mutations (non-coding): 0
- Related genes and loops