- Basic information
- CohesinDB ID: CDBP00419729
- Locus: chr21-40333361-40343594
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE115250, GSE76893, ENCSR404BPV, GSE105028, ENCSR198ZYJ, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, Neurons-H1, TC-32, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, PGR, SOX2, XBP1, FOXA1, SUZ12, HDGF, MEN1, BMI1, CHD7, PRDM1, ZNF444, DPF1, SMARCE1, PAX5, ZNF736, TEAD1, ELF1, ZNF573, ZNF217, ESR1, OCA2, LMO2, JUN, ZNF507, CTCF, EP300, TCF12, MNT, DPF2, RFX5, MED12, RAD51, ZNF512B, E2F1, ZNF528, NR5A2, ZNF350, TEAD4, GTF2F1, PDX1, TFAP2C, POU2F2, CHD8, NANOG, ZSCAN5D, POU5F1, MYCN, ZNF778, KDM4C, TOP2A, CTBP1, ZBTB48, DUX4, STAT1, BAHD1, ERG, ZBTB21, USP7, MYC, EOMES, RFX1, RAD21, GRHL3, STAT3, NKX3-1, RCOR1, NR3C1, CEBPB, CREB1, EZH2, GRHL2, EBF3, TRPS1, ZHX2, ZSCAN2, HDAC2, GATA2, GATAD2B, SREBF1, HCFC1, NCOA2, RUNX1, CBX1, MAFG, SMC1A, NKX2-2, EZH2phosphoT487, BCL6, SIN3A, ZFX, POU4F2, SMAD3, TET2, CREBBP, ZXDC, ZNF384, GR, ARNT, NFIB, ATF2, PRDM9, FOXM1, ETV6, FOS, CHD1, CDK8, MED1, PML, PIAS1, ZMYM3, C11orf30, NCOA1, TBX5, SETDB1, MAFK, USF1, NIPBL, GSPT2, TFAP2A, BCL11A, REST, ATF7, CTBP2, MBD2, FOXP1, BCOR, SMC3, STAG1, MLLT1, FOXA2, ZNF207, TBL1X, MAFF, WT1, HOXB13, KDM1A, YY1, RELA, TARDBP, NEUROD1, SP140, ZIC2, HIF1A, GATA3, MAX, NRIP1, ZNF143, GATA1, MTA1, HAND2, TLE3, KLF4, ZNF592, CEBPG, NCOA3, NR2F2, TCF7L2, NR2F1, KDM5B, ZNF687, PKNOX1, TP53, ZNF334, PHOX2B, T, AR, TAF1, ZNF579, ZBTB40, YAP1, RXR, EGLN2, NCOR1, NOTCH3, BRD4, JUND, CLOCK, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 668
- Number of somatic mutations (non-coding): 0
- Related genes and loops