- Basic information
- CohesinDB ID: CDBP00419732
- Locus: chr21-40353436-40353749
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 83%,
"9_Het": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU5F1, MYCN, KDM4C, ZFX, XBP1, WT1, ZBTB48, STAT1, RELA, CREBBP, MYC, SP140, NRIP1, MED1, EZH2, ESR1, SETDB1, CTCF, BCL11A, AR, HSF1, NOTCH3, STAG1
- Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: Protein_quantitative_trait_loci_(liver)
- Number of somatic mutations (coding): 288
- Number of somatic mutations (non-coding): 50
- Related genes and loops