- Basic information
- CohesinDB ID: CDBP00419733
- Locus: chr21-40354530-40355470
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Data sourse: GSE72082, GSE67783, ENCSR404BPV, GSE206145-NatGen2015, ENCSR198ZYJ, ENCSR703TNG
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Cell type: MCF-7, Fibroblast, Neurons-H1, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 83%,
"9_Het": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CREBBP, GATA2, MAX, MYC, GATA1, CBX1, CREB1, RAD21, POU4F2, ARNT, BRD4, GATA3, TAL1, SMC3, CTCF, ZNF143, AHR
- Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 6
- Related genes and loops